This research is aimed at designing the Ethical Framework for XR (EF4XR) that would guide XR professionals and other stakeholders in the following mission: ensuring the most responsible and enriching use of immersive technologies, particularly those that enable (remote) social interactions and collaborations. The framework would take the form of written guidelines and reports, drafted on the basis of multidisciplinary research with a European focus, as well as derivative activities (e.g. workshops, conferences, panels) aimed at increasing awareness and connecting academics (i.e. social scientists) with tech companies. It is hoped that this research could contribute to creating a well-informed and inclusive dialogue around innovation, thanks to which the XR ecosystem will be better positioned to create experiences that truly enable collective human fulfilment.